AI powered image analysis

Aiforia use cases by application

Over 400 different AI models have been created with Aiforia Create so far, for a multitude of image types (IF, WSI, etc.) and a huge range of therapy areas, research fields, and industrial applications!

Explore some of these examples below!

mHtt

Huntington's Disease

Implementing AI models to analyze mutant huntingtin (mHtt) aggregation in Huntington's Disease affected brain tissue.

Read the case study.

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Astrocytes

Parkinson's Disease

Use of AI for image analysis and astrocyte detection in Parkinson’s Disease research.

Read the case study.

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Iron deposits

Alzheimer's Disease

Measuring the quantity and distribution of iron deposits in grey and white matter in Alzheimer's disease studies at Massachusetts General Hospital.

Read the case study.

 

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α-synuclein

Parkinson's Disease

Quantitative assessment of alpha-synuclein pathology in preclinical Parkinson's disease studies at Lundbeck pharmaceutical company.

Read the case study. 

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TH+ neurons

AI models for the identification and quantification of dopaminergic cells (TH+) in the substantia nigra pars compacta (SNc).

Read the case study.

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Astrocytes

Quantifying astrocyte reactivity in preclinical neurotoxicity studies at Orion pharmaceutical company. 

Read the case study.

 

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Neurons

Parkinson's Disease

Automated neuron quantification for preclinical Parkinson's disease studies at Sanofi.

Read the case study.

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Nigra area

Automated nigra area detection.

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Cultured Neurons

Multichannel Immunofluoresence: somatic and nuclear detection.

Watch video

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Nerve

Classification of nerve components, such as myelin, axon, and nerve fibre.

Watch video

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Cerebellum

Automated classification of molecular and purkinje layers in brain image with area measurements. Subsequent detection and count of interneurons and purkinje cells.

Watch video

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Whole slide human brain

Grey/White matter segmentation and Neuron/Glia counts in human brain sample.

Watch video

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Motoneuron

Detection of motorneurons in rat biopsy.

Watch video

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Neuroscience

Lundbeck-2

Carcinoma

Colorectal Cancer

AI-assisted segmentation of colorectal carcinoma digitized images to identify prognostic and predictive histologic signatures.

Read the case study.

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PD-L1

Lung Cancer

Automated calculation and scoring of PD-L1 markers in a lung.

Read the case study.

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Mitosis

Mitosis detection and quantification.

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Ki-67

Lung Cancer

Calculating Ki-67 proliferation index for pulmonary carcinoid tumors with AI.

Read the case study.

Ki-67 quantification

T, B, and dendritic cells

Breast Cancer

AI assisted detection of IHC stained CD3+ T-cells, CD20+ B-cells, DC-Lamp+ mature dendritic cells, and Hematoxylin in a HER2+ breast cancer surgical resection.

Watch webinar

Breast cancer_T, B-cells, dendritic cells_before Breast cancer_T, B-cells, dendritic cells_after

Tumor grading

NSCLC

Automating tumor grading in non-small cell lung cancer (NSCLC) studies at MIT.

Read the case study. 

Tumor_grading_MIT_before Tumor_grading_MIT_after

Tumor grading

Breast Cancer

Automated tumor grading in breast cancer biopsies.

Breast cancer_grading_before Breast cancer_grading_after

Tumor grading

Prostate Cancer

Automated tumor grading in prostate cancer biopsies.

Read the case study.

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Biomarker identification

PSC

Identifying novel prognostic biomarkers in primary sclerosing cholangitis (PSC).

Read the case study.

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Ballooning

NAFLD and NASH

AI in studying nonalcoholic fatty liver disease (NAFLD) and its capability to segment structures in liver histology.

Read the case study.

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Fibrosis

NAFLD and NASH

Automated quantification of damage and scarring in liver tissue in nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

Find out more

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Inflammation

NAFLD and NASH

Automated quantification of inflammation in liver tissue in nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

Find out more

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Steatosis

NAFLD and NASH

Automated quantification of fat accumulation in liver tissue in nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

Find out more

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Blast Cells

AI trained to identify blast cells (green) and red blood cells (red).

Read the case study.

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Bone Marrow

AI model used to determine changes in bone marrow cellularity

Read the case study.

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Kidney Tissue

Using AI for detecting the cortex and medulla and reviewing tissues for histopathological lesions in blinded studies.

Read the case study.

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DSS Colitis

DSS-induced colitis AI model showing histopathological lesions.

Read the case study

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Immune Cells

Multichannel (Immunofluorescence) human colon tissue showing staining for various vascular and immune cell markers in addition to epithelium.

Immune Cells in Human Colon

NICD1

Aiforia Create training window showing annotations for NICD1 in multi-channel (Immunofluorescence) human colon tissue, stained with various vascular & immune cell markers in addition to epithelium.

Human Colon Multichannel 1

Tuberculosis

Identifying lesions and quantifying cells at Tufts University.

Read the case study.

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Coronavirus

Analyzing microscopic images of human blood and tissue to identify patterns of COVID-related disease.

Read the case study.

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Neovascular lesions

Preclinical ocular models

Neovascular lesion identification in SD-OCT scans for preclinical model development with the contract research organization Experimentica.

Read the case study.

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Preeclampsia

Placental tissue analysis

Quantification of HLA-G/CK7 ratios for protein expression in preeclampsia research.

Read the case study.

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Malaria

Malaria parasite detection from blood smear.

Read the case study.

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Yeast cells

Detection of intact yeast cells in bright field images.

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Pulmonary fibrosis

Identification and quantification of histopathological features of idiopathic pulmonary fibrosis (IPF) including fibroblast foci, and interstitial and alveolar inflammatory cells

Read the case study. 

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ARDS

Acute respiratory distress syndrome (ARDS) lesion segmentation and cell identification.

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Endometrium

Endometrial epithelium segmentation and leukocute quantification.

Read the case study.

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Estrus cycle

Determining the stages of the estrus cycle in cytological samples.

Read the case study.

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Ovarian follicle

Preclinical studies on identification and quantification of ovarian follicles.
 
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Sperm

Identification of sperm cells.

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Lung Fibrosis

Charles River Laboratories pathologists are enhancing image analysis in pre-clinical toxicology, lung studies for lung tissue detection, parenchyma, structural collagen, and fibrotic lesions.

Read the case study.

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Blood Sample

White blood cell (WBC) count.

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Skin Biopsy

Automated detection of dermis and epidermis of skin tissue sample.

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Pancreas

Islet and beta cell classification.

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Other Diseases

Lauren Prince1

Barley

Whole image instance segmentation of barley, including identification of protein matrix, starch, and cell wall. 

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Yeast contaminants

AI-aided identification of contamination in yeast fermentations

Read the case study.

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Salmon skin

Scientists at Nofima used AI to recognize and analyze the successive tissues in Atlantic salmon skin for food safety studies.

Read the case study.

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Concrete

Measuring concrete porosity and composition.

Concrete AI detection

Other Industries

Nofima-use-case-website-2-1

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