Scientific Publications

Virchows Archiv

Digital pathology structure and deployment in Veneto: a proof-of-concept study

Archives of Pathology & Laboratory Medicine

Democratizing Artificial Intelligence in Anatomic Pathology


Manually pressurized droplet digital PCR chip for rapid SARS-CoV-2 diagnostics

Clinical Cancer Research

Improved risk stratification scheme for mismatch repair proficient stage II colorectal cancers using the digital pathology biomarker QuantCRC

Hepatology Communications

Deep learning quantification reveals a fundamental prognostic role for ductular reaction in biliary atresia

Nat Genet.

Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity

Front. Cell. Infect. Microbiol.

Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi


MYC protein is a high-risk factor in mantle cell lymphoma and identifies cases beyond morphology, proliferation and TP53/p53 - a Nordic Lymphoma Group study


Comparative Evaluation of Breast Ductal Carcinoma Grading: A Deep-Learning Model and General Pathologists’ Assessment Approach


Core Needle Biopsy Guidance Based on Tissue Morphology Assessment with AI-OCT Imaging

Frontiers in Molecular Neuroscience

Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling

The American Journal of Pathology

Deep learning based image analysis of liver steatosis in mouse models

Scientific Reports

Development and evaluation of deep learning algorithms for assessment of acute burns and the need for surgery

Scientific Reports

Beneficial behavioral effects of chronic cerebral dopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington’s disease


Automated assessment of Ki-67 proliferation index in neuroendocrine tumors by deep learning

BMC Cardiovascular Disorders

High relative amount of nodular calcification in femoral plaques is associated with milder lower extremity arterial disease


A deep learning–based algorithm for tall cell detection in papillary thyroid carcinoma

Hepathology Research

Automated Image Analysis of Keratin 7 Staining Can Predict Disease Outcome in Primary Sclerosing Cholangitis

Acta Neuropathologica Communications

Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Journal of Pathology Informatics

Development and Technical Validation of an Artificial Intelligence Model for Quantitative Analysis of Histopathologic Features of Eosinophilic Esophagitis

Toxicologic Pathology

Deep Learning-Based Segmentation of Morphologically Distinct Rat Hippocampal Reactive Astrocytes After Trimethyltin Exposure


Quantitative pathologic analysis of digitized images of colorectal carcinoma improves prediction of recurrence free survival

Frontiers in Cellular Neuroscience

A novel automated morphological analysis of Iba1+ microglia using a deep learning assisted model


AI Model for Prostate Biopsies Predicts Cancer Survival

Aiforia Technologies Plc has received funding from the EU H2020 programme.

Brain Communications

Evaluation of ABT-888 in the amelioration of α-synuclein fibril-induced neurodegeneration

Science Translational Medicine

Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer’s disease


Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids


Development and validation of a supervised deep learning algorithm for automated whole-slide programmed death-ligand 1 tumour proportion score assessment in non-small cell lung cancer

Aiforia Technologies Plc has received funding from the EU H2020 programme.

Toxicologic Pathology

Developing a Qualification and Verification Strategy for Digital Tissue Image Analysis in Toxicological Pathology


MicroRNA-7 Protects Against Neurodegeneration Induced by α-Synuclein Preformed Fibrils in the Mouse Brain


Differential impact of clinicopathological risk factors within the 2 largest ProMisE molecular subgroups of endometrial carcinoma

Cell Reports Medicine

Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments

Nature Cancer

Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer

Scientific Reports

Artificial intelligence-based image analysis can predict outcome in high-grade serous carcinoma via histology alone

Acta Neuropathologica Communications

Deep learning assisted quantitative assessment of histopathological markers of Alzheimer’s disease and cerebral amyloid angiopathy

Neurobiology of Aging

Monitoring of a progressive functional dopaminergic deficit in the A53T-AAV synuclein rats by combining 6-[18F]fluoro-L-m-tyrosine imaging and motor performances analysis.

PLoS Pathogens

Hantavirus infection-induced B cell activation elevates free light chains levels in circulation

Molecular and Cellular Neuroscience

Parvalbumin subtypes of cerebellar Purkinje cells contribute to differential intrinsic firing properties

Inflammatory Bowel Diseases

Utilizing Deep Learning to Analyze Whole Slide Images of Colonic Biopsies for Associations Between Eosinophil Density and Clinicopathologic Features in Active Ulcerative Colitis

Journal of Parkinson's Disease

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats

Toxicologic Pathology

Screening For Bone Marrow Cellularity Changes in Cynomolgus Macaques in Toxicology Safety Studies Using Artificial Intelligence Models


Deep neural network analysis - a paradigm shift for histological examination of health and welfare of farmed fish

Toxicologic Pathology

Proof of Concept for a Deep Learning Algorithm for Identification and Quantification of Key Microscopic Features in the Murine Model of DSS-Induced Colitis


Development and initial validation of a deep learning algorithm to quantify histologic features in colorectal carcinoma including tumour budding/poorly differentiated clusters

PLoS Pathogens

Monocyte subset redistribution from blood to kidneys in patients with Puumala virus caused hemorrhagic fever with renal syndrome

Diagnostic Pathology

Chronic cholestasis detection by a novel tool: automated analysis of cytokeratin 7-stained liver specimens

Jama Network Open

Point-of-Care Digital Cytology With Artificial Intelligence for Cervical Cancer Screening in a Resource-Limited Setting

The Journal of Pathology

High tumor cell platelet-derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma

International Journal of Molecular Sciences

Glucocerebrosidase Gene Therapy Induces Alpha-Synuclein Clearance and Neuroprotection of Midbrain Dopaminergic Neurons in Mice and Macaques

Journal of Parkinson's Disease

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats

Human Pathology

Artificial intelligence identifies inflammation and confirms fibroblast foci as prognostic tissue biomarkers in idiopathic pulmonary fibrosis

Nature Cancer

Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1


Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia


Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy

Alimentary Pharmacology and Therapeutics

Evaluating the optimum number of biopsies to assess histological inflammation in ulcerative colitis: a retrospective cohort study


A novel deep learning-based point-of-care diagnostic method for detecting Plasmodium falciparum with fluorescence digital microscopy

Frontiers in Cardiovascular Medicine

Osteoid metaplasia in femoral artery plaques is associated with the clinical severity of lower extremity artery disease in men


Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis

BMC Medical Education

Using online game-based platforms to improve student performance and engagement in histology teaching

Breast Cancer Research and Treatment

Breast cancer outcome prediction with tumour tissue images and machine learning


Detection of breast cancer lymph nodemetastases in frozen sections with a point-ofcare low-cost microscope scanner

Journal of Clinical Pathology

Deep learning for detecting tumour-infiltrating lymphocytes in testicular germ cell tumours

Journal of Neuroscience Research

Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson’s disease

European Urology Focus

PTEN Loss but Not ERG Expression in Diagnostic Biopsies Is Associated with Increased Risk of Progression and Adverse Surgical Findings in Men with Prostate Cancer on Active Surveillance


Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB


Implementation of deep neural networks to count dopamine neurons in substantia nigra

Tumor Biology

The prognostic significance of tall cells in papillary thyroid carcinoma: A case-control study


Reliability of histologic assessment in patients with eosinophilic oesophagitis

Med Ed Publish

Student-focused virtual histology education: Do new scenarios and digital technology matter?

Global Health Action

Point-of-care mobile digital microscopy and deep learning for the detection of soil-transmitted helminths and Schistosoma haematobium

Journal of Pathology Informatics

Antibody-supervised deep learning for quantification of tumor-infiltrating immune cells in hematoxylin and eosin stained breast cancer samples


Quantification of Estrogen Receptor-Alpha Expression in Human Breast Carcinomas With a Miniaturized, Low-Cost Digital Microscope: A Comparison with a High-End Whole Slide-Scanner

Journal of Pathology Informatics

Exploring viewing behavior data from whole slide images to predict correctness of students’ answers during practical exams in oral pathology

Journal of Clinical Pathology

Assessment of tumour viability in human lung cancer xenografts with texture-based image analysis

Diagnostic Pathology

Students' performance during practical examination on whole slide images using view path tracking


A Malaria Diagnostic Tool Based on Computer Vision Screening and Visualization of Plasmodium falciparum Candidate Areas in Digitized Blood Smears

Cerba Research

Evidence for the utility of artificial intelligence (AI) and image analysis in Ki-67 quantification in solid tumors

Mayo Clinic

Clinical Validation and Implementation of an Artificial Intelligence Model for Digital Analysis of Ki-67 Biomarker in Breast Cancer

Mayo Clinic

Additional Validation of a Deep Learning Algorithm to Quantify Histologic Features in Colorectal Carcinoma

Mayo Clinic

Development of an Artificial Intelligence Model for the Evaluation of Histopathologic Features of Eosinophilic Esophagitis

Novartis and University of Basel

AI(H): Deep Learning Model for Staging and Grading Autoimmune Hepatitis from Histology

Charles River Laboratories

Artificial Intelligence Enables Efficient and Reproducible Quantitative Rodent Toxicology Ovarian Follicle Evaluation

University of Helsinki

A Deep Learning Algorithm to Quantify Liver Fat Content in Humans


Systemically administered Aflibercept protects against the development of neovascular lesions in the mouse laser-induced choroidal neovascularization model

Haukeland University Hospital

Using deep neural networks to count Ki-67 positive cells in neuroendocrine tumors

University of Helsinki

Deep convolutional neural network-based method for quantification of the pancreatic β-cell mass in mice

University of Helsinki

Implementation of Neural Networks for studies of brain pathology in Parkinson´s disease

University of Helsinki

Deep-learning neural network in prostate cancer detection and grading

University of Helsinki

A deep-learning algorithm to determine liver fat content in non-alcoholic fatty liver disease in humans