News and reflections from the world of AI

Interview with Dr. Talat Zehra: digital pathology & AI in Pakistan

Tell us a bit about yourself. I have been working in a medical university for the last five years and teach pathology to students in medicine and dentistry disciplines. I am also affiliated with the Jinnah Sindh Medical University (JSMU) lab.

Benefits of AI and digital pathology to the clinical lab: interview with pathologists Dr. Mirtti and Dr. Sandeman

Pathologists have been examining glass slides under a microscope for over 150 years. Only recently did laboratories around the world start digitizing their slides, enabling more efficient workflows and increased accuracy in diagnostics. Adding AI to the newly digitized practice has the potential to increase these benefits exponentially. In this interview pathologists from Sweden and Finland share ...

Interview with Dr. Marika Kangasniemi: AI in endometrial cell analysis

Introduction PEDEGO, a research unit at the University of Oulu, covers a wide range of topics primarily around pediatrics, obstetrics, and gynecology. The metabolic health group within this unit has several ongoing clinical trials related to reproductive and metabolic health in women, including the function of the endometrium in women with polycystic ovary syndrome (PCOS). PCOS affects 10-18% of ...

Validation of PD-L1 AI model launches in six labs across the Netherlands

Introduction  Programmed death-ligand 1 (PDL1) is a protein that, when attached to T cells, prevent the immune system from killing cancer cells. Hence, PDL1 is used as a biomarker for tumor immune escape, a sign of increasing cancer progression. PDL1 percentage is also a significant predictor for immunotherapy efficacy, whereby immune checkpoint inhibitors bind to PDL1 and block its ability to ...

Interview with Dr. Rish Pai on using AI to study colorectal cancer

Introduction Colorectal cancer is the third most common cancer in the United States and pathologists are becoming increasingly valuable in the management of these patients. Analysis of histological features of the tumors is the main source of data for diagnosis, but there are many components to this. Routine pathologic assessment does not capture a quantitative view of the extensive variability ...

Case study: AI model for DSS-induced colitis

Inflammatory Bowel Disease (IBD) is a debilitating disease for which no cures exists. Murine models are widely used to study IBD, amongst them, the DSS-colitis model is a rapid and reliable one. However the scoring of histopathological lesions is challenging. We interviewed veterinary pathologists at Charles River Laboratories, Dr. Agathe Bedard and Dr. Aleksandra Zuraw, on their recently ...