News and reflections from the world of AI

Benefits of AI in preclinical studies

The preclinical phase of drug discovery involves extensive safety evaluations of the potential therapeutic intervention, often using cell and animal models of disease. These studies commonly include going through numerous histopathological samples. This contributes to the drug development process being time-consuming and labor-intensive for pharmaceutical and contract research organizations.

AI-assisted image analysis of neurodegenerative disease markers

Introduction Alzheimer’s disease (AD) is the most common cause of dementia, attributed to its characteristic symptoms of brain shrinkage and cell death. Onset of the diseases is thought to be due to abnormal buildup of amyloid-β (Aβ), a protein in the brain, creating plaques and leading to neurodegeneration. Similarly, Aβ buildup can cause cerebral amyloid angiopathy (CAA), a condition which ...

Christina Caira reflects on use of AI in Parkinson’s disease research

Introduction Parkinson’s disease (PD) is the second most common neurodegenerative disorder, characterized by the degeneration of dopamine releasing regions in the brain. The loss of dopamine leads to a chronic and progressive decrease in movement, coordination, and cognition. While there is no cure, an early diagnosis promotes treatment efficacy and prolongs a higher quality of life

Aiforia signs agreement with South Korean biotech company to augment its novel drug discovery platform with AI

The two companies announced an agreement to add Aiforia’s artificial intelligence technology to Genuv’s ATRIVIEW® proprietary drug discovery platform, used to screen both existing drugs and new substances for neuroprotective and neuroregenerative effects. ATRIVIEW® was used to discover Genuv’s leading drug candidate, SNR1611, which has shown the ability to restore CNS function in preclinical ...

Customer case studies collection: Aiforia Education

Professor of Veterinary Pathology at Norwegian University of Life Sciences (NMBU) Medical schools typically teach histology in the first years but competing pressures on curricula subjects have forced many educators to reduce the amount of time dedicated to normal histology. Additionally, the maintenance of numerous microscopes and slides for teaching purposes is expensive. Using fewer ...

Use of AI for identification and research of orthohantavirus infections

Introduction Orthohantaviruses are globally spread zoonotic pathogens typically causing chronic asymptomatic infection in rodents. However, humans can be infected through contact with rodent urine, saliva, or feces, causing severe health consequences, such as hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). The mechanisms of the virus, though, are unclear.